Henning Stahlberg

Henning Stahlberg

University of Basel, Switzerland

Henning Stahlberg studied solid-state physics at the Technical University of Berlin in Germany, and received his PhD for structural studies of bacterial photosynthesis membrane proteins from the Federal High-School in Lausanne, Switzerland in 1997. Following a PostDoctoral position at the Biozentrum of the University of Basel, Switzerland, in the group of Prof. Andreas Engel, he obtained his Habilitation in Structural Biology in 2002 for structural studies of membrane proteins by cryo-electron microscopy. From 2003 to 2009, he was an Assistant and later Associate Professor at the University of California at Davis (UC Davis) in California, USA, where he developed methods for membrane protein structure determination by cryo-EM. In 2009, he became a Full Professor at the University of Basel, Switzerland, where he is directing the Center for Cellular Imaging and NanoAnalytics (C-CINA).  

His group in Basel is studying the structure and function of ion channel and ion transporter membrane proteins by cryo-electron microscopy. The Stahlberg team is developing several approaches to membrane protein analysis, including sample preparation, imaging protocols, and data analysis tools. His group is developing the 2dx software package for user-friendly image processing of membrane protein cryo-EM data by Fourier-based and by single-particle based algorithms, and the lab is also developing the Dynamo software for sub-volume averaging of large numbers of membrane protein structures from electron tomography data. Investigated membrane protein systems include potassium and chloride channels, and symporters, and secretion systems.

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03 Aug 2014

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