Ilme Schlichting

Schlichtingphoto

Max Planck Institute for Medical Research, Heidelberg, Germany

Ilme Schlichting heads the Depart. of Biomolecular Mechanisms at the Max Planck Institute for Medical Research in Heidelberg. After obtaining her Ph.D. with Kenneth Holmes she moved to Brandeis University to postdoc with Gregory Petsko. Subsequently she became a group leader in Roger Goody’s department at the MPI of Molecular Physiology in Dortmund. Schlichting’s research aims at understanding how proteins achieve their unique functional properties. Key insight is obtained from structures of reaction intermediates. Schlichting was the first to successfully combine photolysis of caged compounds and Laue crystallography to study GTP hydrolysis by the Ras protein, to observe ligand binding intermediates in myoglobin, and to resolve the reaction intermediates of a cytochrome P450 at high spatial resolution. Her latest interests include the application of free-electron laser radiation for structural biology. 

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03 Aug 2014

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